Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528430 | 0.84 | RECQL (0.42) | MAPTRECQLPOLBGAAKMT2A | |
| SCHEMBL9843165 | 0.81 | RECQL (0.40) | MAPTRECQLPOLBGAAKMT2A | |
| Clothianidine SCHEMBL21215 | 0.80 | RECQL (0.39) | MAPTRECQLPOLBGAAKMT2A | |
| Clothianidine SCHEMBL312742 | 0.80 | RECQL (0.39) | MAPTRECQLPOLBGAAKMT2A | |
| SCHEMBL8198330 | 0.79 | MAPT (0.38) | MAPTRECQLPOLBGAAKMT2A | |
| SCHEMBL31668878 | 0.77 | KMT2A (0.37) | MAPTPOLBGAAKMT2AMEN1 | |
| SCHEMBL31668879 | 0.77 | KMT2A (0.37) | MAPTPOLBGAAKMT2AMEN1 | |
| SCHEMBL1527003 | 0.77 | RECQL (0.39) | MAPTRECQLPOLBGAAKMT2A | |
| SCHEMBL7671870 | 0.75 | MAPT (0.42) | MAPTRECQLPOLBGAAKMT2A | |
| SCHEMBL8198326 | 0.75 | MAPT (0.42) | MAPTRECQLPOLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166164-A | Nontoxic to mammals, fish, and crustaceans; nonphytotoxic | AGRO-KANESHO CO., LTD. (JP) | 1992-11-24 | — | — | US | claimed |
| EP-0425978-A2 | Nitroguanidine compounds and insecticides | AGRO-KANESHO CO., LTD. (JP) | 1991-05-08 | — | — | EP | claimed |
| US-5166164-A | Nontoxic to mammals, fish, and crustaceans; nonphytotoxic | AGRO-KANESHO CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0425978-A2 | Nitroguanidine compounds and insecticides | AGRO-KANESHO CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |