Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728499 | 0.84 | MAPT (0.41) | RECQLMAPTATG4BPOLBGAA | |
| SCHEMBL9843165 | 0.82 | RECQL (0.40) | RECQLMAPTPOLBGAAKMT2A | |
| Clothianidine SCHEMBL312742 | 0.81 | RECQL (0.39) | RECQLMAPTPOLBGAAKMT2A | |
| Clothianidine SCHEMBL21215 | 0.81 | RECQL (0.39) | RECQLMAPTPOLBGAAKMT2A | |
| SCHEMBL8198330 | 0.80 | MAPT (0.38) | RECQLMAPTATG4BPOLBGAA | |
| SCHEMBL31742336 | 0.78 | L3MBTL1 (0.43) | RECQLMAPTGAAKMT2AKDM4E | |
| SCHEMBL8198326 | 0.77 | MAPT (0.42) | RECQLMAPTATG4BPOLBGAA | |
| SCHEMBL7671870 | 0.77 | MAPT (0.42) | RECQLMAPTATG4BPOLBGAA | |
| SCHEMBL20659199 | 0.76 | SMN1; SMN2 (0.45) | RECQLMAPTKMT2AKDM4EMEN1 | |
| SCHEMBL12076964 | 0.74 | POLB (0.46) | RECQLMAPTPOLBKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873325-A1 | PROCESS FOR PRODUCING GUANIDINE DERIVATIVES, INTERMEDIATES THEREFOR AND THEIR PRODUCTION | Takeda Chemical Industries, Ltd. (JP) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997000867-A1 | PROCESS FOR PRODUCING GUANIDINE DERIVATIVES, INTERMEDIATES THEREFOR AND THEIR PRODUCTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-09 | — | — | WO | disclosed |