Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005497 | 0.78 | GBA1 (0.36) | USP30ALOX5CHRM2CHRM1CHRM3 | |
| SCHEMBL7290370 | 0.78 | GBA1 (0.36) | USP30ALOX5CHRM2CHRM1CHRM3 | |
| SCHEMBL1981228 | 0.78 | GBA1 (0.36) | USP30ALOX5CHRM2CHRM1CHRM3 | |
| SCHEMBL7292836 | 0.76 | USP30 (0.40) | USP30L3MBTL1 | |
| SCHEMBL7333182 | 0.76 | USP30 (0.40) | USP30L3MBTL1 | |
| SCHEMBL3594424 | 0.75 | MEN1 (0.36) | USP30 | |
| SCHEMBL3610281 | 0.74 | ALOX5 (0.38) | USP30ALOX5CHRM2CHRM1CHRM3 | |
| SCHEMBL9057454 | 0.74 | ALOX5 (0.38) | USP30ALOX5CHRM2CHRM1CHRM3 | |
| SCHEMBL9382586 | 0.74 | SMN1; SMN2 (0.41) | CHRM2CHRM1CHRM3LMNASMN1; SMN2 | |
| SCHEMBL642839 | 0.74 | SMN1; SMN2 (0.41) | CHRM2CHRM1CHRM3LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169833-A | Analgesics | G. D. SEARLE & CO. (US) | 1992-12-08 | — | — | US | disclosed |