Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | ALPL | P05186 | 1/20 | 0.69 |
| ▸ | ALPI | P09923 | 1/20 | 0.69 |
| ▸ | ALPG | P10696 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728720 | 0.87 | ALDH1A1 (0.74) | EPHX1ALDH1A1CYP1A2ALPLALPI | |
| SCHEMBL14855627 | 0.84 | POLB (0.79) | KDM4EMEN1KMT2AMAPTPOLB | |
| N-(Phenylcarbamothioyl)Benzamide SCHEMBL2341910 | 0.84 | EPHX1 (1.00) | EPHX1ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL6118209 | 0.84 | EPHX1 (0.78) | EPHX1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9728074 | 0.84 | ALDH1A1 (0.70) | EPHX1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11165411 | 0.81 | ALDH1A1 (0.71) | EPHX1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL18550720 | 0.78 | NPC1 (0.71) | EPHX1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL31741297 | 0.78 | NPC1 (0.71) | EPHX1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8613625 | 0.78 | EPHX1 (0.76) | EPHX1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27451748 | 0.78 | MIF (0.83) | EPHX1ALDH1A1CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |