Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.41 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728630 | 1.00 | GAA (0.44) | GAAALDH1A1MAPK1L3MBTL1NPFFR1 | |
| SCHEMBL9727808 | 0.86 | GAA (0.48) | GAAALDH1A1MAPK1L3MBTL1NPFFR1 | |
| SCHEMBL9727869 | 0.86 | GAA (0.48) | GAAALDH1A1MAPK1L3MBTL1NPFFR1 | |
| SCHEMBL9205704 | 0.86 | GAA (0.48) | GAAALDH1A1MAPK1L3MBTL1NPFFR1 | |
| SCHEMBL9728346 | 0.86 | GAA (0.48) | GAAALDH1A1MAPK1L3MBTL1NPFFR1 | |
| SCHEMBL9728425 | 0.86 | GAA (0.48) | GAAALDH1A1MAPK1L3MBTL1NPFFR1 | |
| SCHEMBL9199841 | 0.86 | GAA (0.48) | GAAALDH1A1MAPK1L3MBTL1NPFFR1 | |
| SCHEMBL9207326 | 0.86 | TDP1 (0.42) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL10367536 | 0.84 | GAA (0.46) | GAAALDH1A1MAPK1L3MBTL1NPFFR1 | |
| SCHEMBL10367534 | 0.84 | GAA (0.46) | GAAALDH1A1MAPK1L3MBTL1NPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122604-A | 2-(2-Carbonyl-substituted pyrrolidin-4-yl)carbapenems and -penems; microbiocides | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| US-4943569-A | B-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4933333-A | β-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0126587-A1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-11-28 | — | — | EP | disclosed |