Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728630 | 0.86 | GAA (0.44) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9728638 | 0.86 | GAA (0.44) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10390211 | 0.84 | TDP1 (0.46) | TDP1ATMRAB9AMAOB | |
| SCHEMBL8437949 | 0.84 | TDP1 (0.42) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8437950 | 0.84 | TDP1 (0.42) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10390212 | 0.84 | TDP1 (0.46) | TDP1ATMRAB9AMAOB | |
| SCHEMBL17446838 | 0.84 | TDP1 (0.50) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10513485 | 0.84 | TDP1 (0.41) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8436015 | 0.84 | TDP1 (0.41) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10513490 | 0.84 | TDP1 (0.41) | TDP1ATMALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126587-B1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMA (JP) | 1995-04-19 | — | — | EP | disclosed |