Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23037 | 0.87 | CRHR1 (0.38) | EGFRCHRM4LMNARPS6KB1CRHR1 | |
| SCHEMBL9728774 | 0.84 | EGFR (0.38) | EGFRLMNARPS6KB1CRHR1P2RX3 | |
| SCHEMBL9729841 | 0.84 | EGFR (0.41) | EGFRCHRM4MEN1KMT2AP2RX3 | |
| SCHEMBL9193841 | 0.79 | CRHR1 (0.39) | EGFRRPS6KB1CRHR1MEN1KMT2A | |
| SCHEMBL8025137 | 0.79 | EGFR (0.37) | EGFRRPS6KB1CRHR1MEN1KMT2A | |
| SCHEMBL9729074 | 0.77 | JAK2 (0.38) | EGFRCHRM4LMNACRHR1ALDH1A1 | |
| SCHEMBL9729031 | 0.74 | EGFR (0.36) | EGFRLMNARPS6KB1CRHR1 | |
| SCHEMBL9728735 | 0.73 | EGFR (0.39) | EGFRCHRM4CRHR1MEN1KMT2A | |
| SCHEMBL9765693 | 0.72 | CRHR1 (0.36) | LMNACRHR1MEN1KMT2AALDH1A1 | |
| SCHEMBL8286106 | 0.71 | MAPK1 (0.42) | LMNAMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141941-A | ARALKYLAMINE DERIVATIVES, AND FUNGICIDES CONTAINING THE SAME | UBE INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | claimed |