SCHEMBL9728771

SCHEMBL9728771

Fc1cccc(Cl)c1-c1ccc(Cl)[c]c1Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.34
PTGES O14684 5/20 0.34
JAK2 O60674 1/20 0.34
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PBRM1 Q86U86 3/20 0.33
SMARCA2 P51531 2/20 0.33
SMARCA4 P51532 2/20 0.33
GAA P10253 1/20 0.33
EIF4E P06730 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PDE2A O00408 1/20 0.31
PDE10A Q9Y233 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15636867 0.91 CA1 (0.32)
SCHEMBL1815221 0.87 FGFR1 (0.33) LMNACYP1A2
SCHEMBL15636973 0.76 CA1 (0.32)
SCHEMBL1982000 0.76 KDM4E (0.35) SMN1; SMN2
SCHEMBL17514576 0.74 HTR5A (0.31)
SCHEMBL31067193 0.72 PBRM1 (0.44) TAAR1PTGESJAK2LMNAMAPK1
SCHEMBL5047787 0.72 CD44 (0.35) MAPK1SMN1; SMN2CYP1A2
SCHEMBL3873200 0.72 NOTUM (0.37) MAPK1
SCHEMBL17514673 0.71
SCHEMBL17514752 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5164408-A Triazole compounds, fungicides BASF AKTIENGESELLSCHAFT (DE) 1992-11-17 US disclosed