Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329300 | 0.71 | MAPT (0.66) | MAPTMEN1KMT2ABCHEDRD2 | |
| SCHEMBL1374365 | 0.70 | POLB (0.73) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| Hydrochloric Acid SCHEMBL693073 | 0.69 | MAPT (0.63) | MAPTMEN1KMT2ABCHEDRD2 | |
| SCHEMBL9768710 | 0.69 | MAPT (0.63) | MAPTMEN1KMT2ABCHEDRD2 | |
| Bromide SCHEMBL11611692 | 0.69 | MAPT (0.63) | MAPTMEN1KMT2ABCHEDRD2 | |
| Water SCHEMBL28273899 | 0.69 | MAPT (0.63) | MAPTMEN1KMT2ABCHEDRD2 | |
| SCHEMBL28789751 | 0.69 | SLC2A1 (0.51) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL9485158 | 0.68 | MAPT (0.61) | MAPTMEN1KMT2ABCHEDRD2 | |
| SCHEMBL172516 | 0.68 | MAPT (0.60) | MAPTMEN1KMT2ABCHEDRD2 | |
| SCHEMBL13532663 | 0.67 | MAPT (0.61) | MAPTMEN1KMT2ABCHEDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162360-A | Treating hypercholesterolemia and atherosclerosis; ACAT acyl-coenzyme A:-cholesterol acyltransferase | WARNER-LAMBERT COMPANY (US) | 1992-11-10 | — | — | US | disclosed |