Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622694 | 0.70 | KDM4E (0.32) | KDM4ENPC1ALDH1A1LMNAGAA | |
| SCHEMBL4335211 | 0.62 | — | — | |
| SCHEMBL37435600 | 0.60 | CYP1A2 (0.36) | KDM4ENPC1ALDH1A1LMNAGAA | |
| SCHEMBL10977948 | 0.58 | MEN1 (0.36) | KDM4EALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL15549945 | 0.58 | KDM4E (0.36) | KDM4ENPC1ALDH1A1LMNAGAA | |
| SCHEMBL974163 | 0.58 | CYP1A2 (0.36) | KDM4ENPC1ALDH1A1LMNAGAA | |
| SCHEMBL9279571 | 0.58 | KDM4E (0.45) | KDM4ENPC1ALDH1A1LMNAGAA | |
| SCHEMBL1357123 | 0.56 | IDO1 (0.31) | — | |
| SCHEMBL29699894 | 0.56 | NTSR1 (0.33) | KDM4E | |
| SCHEMBL29913884 | 0.56 | IDO1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104980-A | CHROMOGENIC DIBENZOXAZEPINONE AND DIBENZOTHIAZEPINONE ENZYME SUBSTRATES | MILES INC. (US) | 1992-04-14 | — | — | US | disclosed |