Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.65 |
| ▸ | PIM1 | P11309 | 5/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25973846 | 0.88 | KDM4E (0.78) | KDM4EALDH1A1HPGDMAPTNTRK1 | |
| SCHEMBL9537611 | 0.83 | KDM4E (0.71) | KDM4EALDH1A1HPGDMAPTNTRK1 | |
| SCHEMBL8768671 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1HPGDMAPTNTRK1 | |
| SCHEMBL3418501 | 0.76 | KDM4E (0.61) | KDM4EALDH1A1HPGDMAPTNTRK1 | |
| SCHEMBL3296447 | 0.76 | KDM4E (0.61) | KDM4EALDH1A1HPGDNTRK1PIM1 | |
| SCHEMBL10843180 | 0.75 | POLB (0.62) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL8822991 | 0.75 | KMT2A (0.66) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL9534772 | 0.72 | KDM4E (0.56) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL10842278 | 0.70 | POLB (0.58) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL29283642 | 0.70 | NTRK1 (0.81) | KDM4EALDH1A1HPGDMAPTNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169850-A | Neurotropic or hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| US-5059691-A | Anxiolytic agents; hypotensive agents; nervous system disorders; cognition activators | AMERICAN CYANAMID COMPANY (US) | 1991-10-22 | — | — | US | disclosed |