Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17842003 | 0.84 | IDO1 (0.43) | IDO1TDO2GAAHDAC4ALDH1A1 | |
| SCHEMBL3999911 | 0.84 | IDO1 (0.55) | IDO1TDO2DPP4GAACES2 | |
| SCHEMBL17842282 | 0.81 | ADRB2 (0.42) | IDO1TDO2GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL32690499 | 0.79 | IDO1 (0.43) | IDO1TDO2GAAALDH1A1LMNA | |
| SCHEMBL17842404 | 0.79 | IDO1 (0.47) | IDO1TDO2GAAMEN1KMT2A | |
| SCHEMBL4505743 | 0.78 | DPP4 (0.51) | HTR2AIDO1TDO2DPP4KMT2A | |
| SCHEMBL694825 | 0.77 | IDO1 (0.41) | IDO1TDO2GAAMEN1KMT2A | |
| SCHEMBL16111744 | 0.77 | HTR2A (0.37) | HTR2AIDO1TDO2DPP4GAA | |
| SCHEMBL16111990 | 0.77 | IGF1R (0.42) | HTR2AIDO1TDO2GAAIGF1R | |
| SCHEMBL327420 | 0.76 | IDO1 (0.51) | HTR2AIDO1TDO2GAAIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081241-A | Diabetes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |