Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251804 | 0.80 | TNF (0.56) | TNF | |
| SCHEMBL2330664 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4E | |
| SCHEMBL9729047 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EGSK3AGSK3BMEN1 | |
| SCHEMBL29451873 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EGSK3AGSK3BMEN1 | |
| SCHEMBL239409 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EGSK3AGSK3BL3MBTL1 | |
| SCHEMBL18348924 | 0.74 | ALDH1A1 (0.69) | ALDH1A1KDM4EGSK3AGSK3BMEN1 | |
| SCHEMBL13414108 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4E | |
| SCHEMBL9729840 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KDM4EGSK3AGSK3BMEN1 | |
| SCHEMBL6305749 | 0.72 | ALDH1A1 (0.64) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL23723363 | 0.70 | ALDH1A1 (0.68) | ALDH1A1KDM4EGSK3AGSK3BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175290-A | Bronchodilator, cardiotonic agents | MARION MERRELL DOW INC. (US) | 1992-12-29 | — | — | US | disclosed |