Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 16/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | RAD52 | P43351 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729069 | 1.00 | HTR4 (0.72) | HTR4KCNH2MAPTRAD52ABCB11 | |
| SCHEMBL9729077 | 1.00 | HTR4 (0.72) | HTR4KCNH2MAPTRAD52ABCB11 | |
| Water SCHEMBL9729798 | 0.91 | HTR4 (0.75) | HTR4KCNH2MAPTRAD52ABCB11 | |
| Water SCHEMBL9729783 | 0.91 | HTR4 (0.75) | HTR4KCNH2MAPTRAD52ABCB11 | |
| Water SCHEMBL9729791 | 0.91 | HTR4 (0.75) | HTR4KCNH2MAPTRAD52ABCB11 | |
| SCHEMBL3320031 | 0.91 | HTR4 (0.75) | HTR4KCNH2MAPTRAD52ABCB11 | |
| SCHEMBL3320023 | 0.91 | HTR4 (0.75) | HTR4KCNH2MAPTRAD52ABCB11 | |
| SCHEMBL3320028 | 0.91 | HTR4 (0.75) | HTR4KCNH2MAPTRAD52ABCB11 | |
| Water SCHEMBL9721589 | 0.90 | HTR4 (0.76) | HTR4KCNH2MAPT | |
| Water SCHEMBL9721584 | 0.90 | HTR4 (0.76) | HTR4KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130312-A | Gastrointestinal motility stimulators | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-07-14 | — | — | US | disclosed |
| US-4906643-A | Substituted N-(3-hydroxy-4-piperidinyl)benzamides as gastrointestinal agents | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-03-06 | — | — | US | disclosed |