Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819439 | 1.00 | PPARA (0.51) | PPARAALDH1A1GPR84TLR8MAPT | |
| SCHEMBL9729317 | 1.00 | PPARA (0.51) | PPARAALDH1A1GPR84TLR8MAPT | |
| SCHEMBL9728878 | 1.00 | PPARA (0.51) | PPARAALDH1A1GPR84TLR8MAPT | |
| SCHEMBL9728795 | 1.00 | PPARA (0.51) | PPARAALDH1A1GPR84TLR8MAPT | |
| SCHEMBL4109812 | 1.00 | PPARA (0.51) | PPARAALDH1A1GPR84TLR8MAPT | |
| SCHEMBL9729094 | 1.00 | PPARA (0.51) | PPARAALDH1A1GPR84TLR8MAPT | |
| SCHEMBL4097027 | 1.00 | PPARA (0.51) | PPARAALDH1A1GPR84TLR8MAPT | |
| SCHEMBL4104171 | 0.98 | PPARA (0.49) | PPARAALDH1A1GPR84TLR8MAPT | |
| SCHEMBL1758968 | 0.92 | PPARA (0.43) | PPARATLR8NOS2 | |
| SCHEMBL4112008 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162360-A | Treating hypercholesterolemia and atherosclerosis; ACAT acyl-coenzyme A:-cholesterol acyltransferase | WARNER-LAMBERT COMPANY (US) | 1992-11-10 | — | — | US | disclosed |