Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4104171 | 0.94 | PPARA (0.49) | PPARANOS2TLR8RAB9ANPC1 | |
| SCHEMBL4097027 | 0.92 | PPARA (0.51) | PPARANOS2TLR8 | |
| SCHEMBL9729082 | 0.92 | PPARA (0.51) | PPARANOS2TLR8 | |
| SCHEMBL9819439 | 0.92 | PPARA (0.51) | PPARANOS2TLR8 | |
| SCHEMBL9729317 | 0.92 | PPARA (0.51) | PPARANOS2TLR8 | |
| SCHEMBL9729094 | 0.92 | PPARA (0.51) | PPARANOS2TLR8 | |
| SCHEMBL9728795 | 0.92 | PPARA (0.51) | PPARANOS2TLR8 | |
| SCHEMBL4109812 | 0.92 | PPARA (0.51) | PPARANOS2TLR8 | |
| SCHEMBL9728878 | 0.92 | PPARA (0.51) | PPARANOS2TLR8 | |
| SCHEMBL4112008 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105188383-A | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG | 2015-12-23 | — | — | CN | disclosed |
| EP-2496584-A1 | PROCESS FOR THE PREPARATION OF IMIDAZO[2,1-B][1,3]BENZOTHIAZOLE DERIVATIVES | Ambit Biosciences Corp. (US) | 2012-09-12 | — | — | EP | disclosed |
| EP-2484342-A1 | Hair resiliency / body improver and hair cosmetic | Shiseido Company, Limited (JP) | 2012-08-08 | — | — | EP | disclosed |
| CN-102470127-A | Biaryl compounds and methods of use thereof | AMBIT BIOSCIENCES CORP | 2012-05-23 | — | — | CN | disclosed |
| CN-102216277-A | Substituted benzamides as cannabinoid receptor ligands | ABBOTT LAB | 2011-10-12 | — | — | CN | disclosed |
| WO-2011056939-A1 | PROCESS FOR THE PREPARATION OF IMIDAZO[2,1-B][1,3]BENZOTHIAZOLE DERIVATIVES | AMBIT BIOSCIENCES CORP. (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20090233975-A1 | Hair resiliency/body improver and hair cosmetic | SHISEIDO COMPANY, LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-2063897-A2 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Deciphera Pharmaceuticals, LLC. (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-2063896-A2 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Deciphera Pharmaceuticals, LLC. (US) | 2009-06-03 | — | — | EP | disclosed |
| CN-101232863-A | Agent for improving hair tension and toughness and cosmetic for hair | SHISEIDO CO LTD (JP) | 2008-07-30 | — | — | CN | disclosed |
| EP-1911750-A1 | AGENT FOR IMPROVEMENT IN BOUNCE/BODY OF HAIR, AND HAIR COSMETIC | Shiseido Company, Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
| WO-2008034008-A2 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008033999-A2 | KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-03-20 | — | — | WO | disclosed |
| EP-0282320-B1 | BISPHOSPHONIC ACID DERIVATIVES AND MEDICINES CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4973576-A | ANTIARTHRITIC AGENTS, TREATMENT OF HYPERCALCEMIA | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| EP-0282320-A1 | Bisphosphonic acid derivatives and medicines containing the same | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233975-A1 | Hair resiliency/body improver and hair cosmetic | MC1R, PNISR, HCRTR1 | PPARA 1793/4885NOS2 892/4885TLR8 1508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.