Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.67 |
| ▸ | HTR3A | P46098 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | APEX1 | P27695 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074768 | 0.89 | TAAR1 (0.80) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL7490714 | 0.83 | TAAR1 (0.64) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL10714160 | 0.80 | CYP19A1 (0.46) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL13880000 | 0.80 | TAAR1 (0.67) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| Octopamine SCHEMBL3489184 | 0.80 | TAAR1 (1.00) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL18434948 | 0.80 | CYP19A1 (0.46) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| Octopamine SCHEMBL1650462 | 0.80 | TAAR1 (1.00) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| Octopamine SCHEMBL22605 | 0.80 | TAAR1 (1.00) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL7210158 | 0.78 | TAAR1 (0.64) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL531326 | 0.78 | TAAR1 (0.64) | TAAR1NFKB1TSHRHIF1AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103709116-A | Preparation method for 4-(4-alkoxycarbonylamino)phenyl-3-morpholine | UNIV SICHUAN | 2014-04-09 | — | — | CN | claimed |
| EP-0226072-B1 | OXIDATION DYE CONTAINING 4-AMINO-2-AMINOMETHYL PHENOL | Wella Aktiengesellschaft (DE) | 1991-04-10 | — | — | EP | claimed |
| EP-0146738-B1 | ANTIMICROBIAL ANIMAL FEED ADDITIVE COMPOSITIONS | AMERICAN CYANAMID COMPANY (US) | 1990-12-19 | — | — | EP | claimed |
| EP-0252351-B1 | 5-ALKOXY-2,4-DIAMINO-ALKYLBENZENES AND HAIR DYES CONTAINING SAME | Wella Aktiengesellschaft (DE) | 1990-09-12 | — | — | EP | claimed |
| US-4797130-A | DYE DEVELOPERS GOOD FOR RED COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | claimed |
| EP-0252351-A1 | 5-Alkoxy-2,4-diamino-alkylbenzenes and hair dyes containing same | Wella Aktiengesellschaft (DE) | 1988-01-13 | — | — | EP | claimed |
| US-4713080-A | OXIDATIVE COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | claimed |
| EP-0226072-A1 | Oxidation dye containing 4-amino-2-aminomethyl phenol | Wella Aktiengesellschaft (DE) | 1987-06-24 | — | — | EP | claimed |
| WO-1987003475-A2 | OXIDIZING HAIR DYER BASED ON 4-AMINO-2-AMINOMETHYLPHENOLS | WELLA AKTIENGESELLSCHAFT (DE) | 1987-06-18 | — | — | WO | claimed |
| EP-0182187-A1 | Oxidative dyestuff compositions for dyeing the hair, consisting of 4-amino-2-hydroxyalkyl phenols | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | claimed |
| WO-1986002829-A1 | OXIDATION-TYPE HAIR-DYEING MEANS BASED ON 4-AMINO-2-HYDROXYALKYL-PHENOLS | WELLA AKTIENGESELLSCHAFT (DE) | 1986-05-22 | — | — | WO | claimed |
| EP-0166025-A2 | Non-antibiotic animal feed additive compositions | AMERICAN CYANAMID COMPANY (US) | 1986-01-02 | — | — | EP | claimed |
| EP-0146738-A2 | Antimicrobial animal feed additive compositions | AMERICAN CYANAMID COMPANY (US) | 1985-07-03 | — | — | EP | claimed |
| US-20240216525-A1 | ENZYME-TRIGGERED SELF-REACTING LINKER HAVING IMPROVED PHYSICOCHEMICAL AND PHARMACOLOGICAL PROPERTIES | MABLINK BIOSCIENCE (FR) | 2024-07-04 | — | — | US | disclosed |
| EP-4313157-A1 | ENZYME-TRIGGERED SELF-REACTING LINKER HAVING IMPROVED PHYSICOCHEMICAL AND PHARMACOLOGICAL PROPERTIES | Mablink Bioscience (FR) | 2024-02-07 | — | — | EP | disclosed |
| CN-117157102-A | Enzyme-triggered self-reacting linkers with improved physicochemical and pharmacological properties | 马布林克生物科学公司 | 2023-12-01 | — | — | CN | disclosed |
| EP-0146738-A2 | Antimicrobial animal feed additive compositions | AMERICAN CYANAMID COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |
| EP-0146738-A2 | Antimicrobial animal feed additive compositions | AMERICAN CYANAMID COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |
| US-4119710-A | ANALGESICS, UTEROSPASMOLYTICS, ANTISPASTICS, BLOCKING AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-10-10 | — | — | US | disclosed |
| US-4119710-A | ANALGESICS, UTEROSPASMOLYTICS, ANTISPASTICS, BLOCKING AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216525-A1 | ENZYME-TRIGGERED SELF-REACTING LINKER HAVING IMPROVED PHYSICOCHEMICAL AND PHARMACOLOGICAL PROPERTIES | DDC, BCHE, ENGASE | TAAR1 2170/4885NFKB1 3924/4885TSHR 2759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.