Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 3/20 | 0.33 |
| ▸ | ARG2 | P78540 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 5/20 | 0.33 |
| ▸ | GRM6 | O15303 | 4/20 | 0.33 |
| ▸ | GRM8 | O00222 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2524446 | 0.98 | ARG1 (0.34) | ARG1ARG2GAAEPHX1GRM2 | |
| SCHEMBL30746735 | 0.94 | ARG1 (0.38) | ARG1ARG2GRM2GRM3GRM6 | |
| SCHEMBL76967 | 0.94 | ARG1 (0.38) | ARG1ARG2GRM2GRM3GRM6 | |
| SCHEMBL2730057 | 0.87 | GRM2 (0.40) | GRM2GRM3GRM6GRM8MAPK1 | |
| SCHEMBL2063878 | 0.84 | GAA (0.35) | GAAEPHX1MAPK1HPGDTSHR | |
| SCHEMBL29707789 | 0.82 | MAPK1 (0.34) | GAAEPHX1MAPK1HPGDBTK | |
| SCHEMBL31337843 | 0.81 | MAPK1 (0.33) | GAAEPHX1MAPK1 | |
| SCHEMBL190124 | 0.78 | GRM2 (0.43) | GRM2GRM3GRM6GRM8MAPK1 | |
| SCHEMBL3645961 | 0.78 | MAPK1 (0.36) | GAAEPHX1MAPK1HPGDBTK | |
| SCHEMBL30086083 | 0.78 | GRM2 (0.43) | GRM2GRM3GRM6GRM8MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175146-A | Improved potency; storage stability; nonhydrolyzing; osteoporosis; Paget's disease; hypocalcemic | VICAL, INC. (US) | 1992-12-29 | — | — | US | disclosed |