SCHEMBL9729227

SCHEMBL9729227

OCCNC(c1ccccc1)C(O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.55
MAN2A1 Q16706 2/20 0.47
MAN1B1 Q9UKM7 2/20 0.47
MTOR P42345 1/20 0.42
RAB9A P51151 1/20 0.42
GRM7 Q14831 1/20 0.42
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 2/20 0.41
CYP3A4 P08684 2/20 0.41
ALOX15 P16050 2/20 0.41
TSHR P16473 2/20 0.41
ADRA2C P18825 2/20 0.41
CHRM2 P08172 1/20 0.41
ADRA1A P35348 1/20 0.41
RGS12 O14924 1/20 0.41
GLA P06280 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9728901 0.89 ALDH1A1 (0.54) AOC3MAN2A1MAN1B1MTORRAB9A
SCHEMBL9729228 0.87 AOC3 (0.50) AOC3MAN2A1MAN1B1MTORRAB9A
SCHEMBL9728845 0.86 CNR2 (0.44) AOC3MAN2A1MAN1B1KDM4EALDH1A1
SCHEMBL10523671 0.86 AOC3 (0.49) AOC3MAN2A1MAN1B1MTORRAB9A
SCHEMBL9729174 0.86 AOC3 (0.49) AOC3MAN2A1MAN1B1MTORRAB9A
SCHEMBL9729435 0.83 AOC3 (0.53) AOC3MAN2A1MAN1B1MTORRAB9A
SCHEMBL4651020 0.83 ALDH1A1 (0.44) AOC3MTORRAB9AGRM7KDM4E
SCHEMBL11879421 0.83 AOC3 (0.58) AOC3MAN2A1MAN1B1MTORRAB9A
SCHEMBL4083083 0.83 AOC3 (0.53) AOC3MAN2A1MAN1B1MTORRAB9A
SCHEMBL9729965 0.81 AKT1 (0.43) AOC3MAN2A1MAN1B1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4803200-A SHIPPING FEVER SYNDROME A. H. ROBINS COMPANY, INCORPORATED (US) 1989-02-07 US claimed
US-5171753-A Derivatives of 2-amino-1-phenylethanol having antiulcer activity A. H. ROBINS COMPANY, INCORPORATED (US) 1992-12-15 US disclosed
US-4803200-A SHIPPING FEVER SYNDROME A. H. ROBINS COMPANY, INCORPORATED (US) 1989-02-07 US disclosed