Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8742273 | 0.78 | MAPK1 (0.61) | SMN1; SMN2KMT2AMEN1FKBP1AMAPK1 | |
| SCHEMBL8325065 | 0.76 | KMT2A (0.71) | SMN1; SMN2KMT2AMEN1MAPK1ALOX15 | |
| SCHEMBL30118954 | 0.76 | KMT2A (0.71) | SMN1; SMN2KMT2AMEN1MAPK1ALOX15 | |
| SCHEMBL1528648 | 0.75 | KDM4E (0.74) | SMN1; SMN2TP53RAB9APOLB | |
| SCHEMBL8328048 | 0.74 | KMT2A (0.68) | KMT2AMEN1FKBP1AHTT | |
| SCHEMBL14005042 | 0.72 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AMEN1FKBP1AMAPK1 | |
| SCHEMBL6037483 | 0.71 | FKBP1A (0.58) | SMN1; SMN2KMT2AMEN1FKBP1AMAPK1 | |
| SCHEMBL12766946 | 0.71 | HTT (0.72) | KMT2APOLBPKMNPSR1TSHR | |
| SCHEMBL11209832 | 0.71 | CA12 (0.50) | SMN1; SMN2KMT2AMAPK1TP53RAB9A | |
| SCHEMBL11209836 | 0.71 | MAPT (0.53) | SMN1; SMN2POLBTSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |