Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337920 | 0.89 | KEAP1 (0.57) | USP2KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL734049 | 0.82 | USP2 (0.72) | USP2SMN1; SMN2KDM4EALDH1A1GLA | |
| SCHEMBL12349244 | 0.82 | USP2 (0.54) | USP2KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL15314031 | 0.80 | USP2 (0.52) | USP2KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10506181 | 0.79 | KEAP1 (0.54) | USP2KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| Hydroxyamine SCHEMBL1453894 | 0.79 | USP2 (0.50) | USP2KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27586193 | 0.79 | USP2 (0.50) | USP2KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2779513 | 0.79 | USP2 (0.75) | USP2KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2780188 | 0.79 | USP2 (0.75) | USP2KEAP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL457031 | 0.79 | USP2 (0.75) | USP2KEAP1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171753-A | Derivatives of 2-amino-1-phenylethanol having antiulcer activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-12-15 | — | — | US | disclosed |