Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730130 | 0.89 | KMT2A (0.53) | TACR1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL9729456 | 0.88 | TACR1 (0.59) | TACR1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL9729234 | 0.87 | TACR1 (0.61) | TACR1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL9729686 | 0.87 | TACR1 (0.58) | TACR1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL9730246 | 0.87 | TACR1 (0.58) | TACR1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL9729985 | 0.87 | TACR1 (0.58) | TACR1KMT2AMEN1CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL9729778 | 0.86 | TACR1 (0.57) | TACR1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL9729849 | 0.85 | TACR1 (0.58) | TACR1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL9730595 | 0.85 | TACR1 (0.58) | TACR1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL9729860 | 0.85 | MEN1 (0.53) | TACR1KMT2AMEN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |