Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | ME2 | P23368 | 1/20 | 0.41 |
| ▸ | ME1 | P48163 | 1/20 | 0.41 |
| ▸ | ME3 | Q16798 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730595 | 1.00 | TACR1 (0.58) | TACR1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL9729860 | 0.92 | MEN1 (0.53) | TACR1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL9730103 | 0.92 | MAPT (0.56) | TACR1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL9730126 | 0.90 | TACR1 (0.51) | TACR1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL9729490 | 0.90 | TACR1 (0.48) | TACR1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL9730188 | 0.90 | MAPT (0.48) | TACR1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL9729215 | 0.90 | TACR1 (0.51) | TACR1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL9730176 | 0.90 | TACR1 (0.53) | TACR1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL9730167 | 0.90 | MEN1 (0.51) | TACR1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL9729330 | 0.88 | TACR1 (0.52) | TACR1MEN1KMT2ATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |