Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728886 | 0.90 | CHRNA7 (0.35) | LMNAALDH1A1CHRNA7SLC6A2SLC6A4 | |
| SCHEMBL9728901 | 0.83 | ALDH1A1 (0.54) | LMNAALDH1A1HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL9729725 | 0.83 | AOC3 (0.43) | LMNAALDH1A1HSD17B10SIGMAR1ABCB11 | |
| SCHEMBL9729035 | 0.78 | AOC3 (0.42) | ALDH1A1SIGMAR1CHRM2AOC3CNR2 | |
| SCHEMBL9729228 | 0.78 | AOC3 (0.50) | LMNAALDH1A1HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL9729159 | 0.77 | AOC3 (0.41) | LMNAALDH1A1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL9729075 | 0.77 | AOC3 (0.41) | LMNAALDH1A1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL9729174 | 0.77 | AOC3 (0.49) | LMNAALDH1A1HSD17B10CYP2D6ADRA1A | |
| SCHEMBL10523671 | 0.77 | AOC3 (0.49) | LMNAALDH1A1HSD17B10CYP2D6ADRA1A | |
| SCHEMBL9729965 | 0.72 | AKT1 (0.43) | ALDH1A1SLC6A2SLC6A4CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803200-A | SHIPPING FEVER SYNDROME | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-02-07 | — | — | US | claimed |
| US-5171753-A | Derivatives of 2-amino-1-phenylethanol having antiulcer activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-12-15 | — | — | US | disclosed |
| US-4803200-A | SHIPPING FEVER SYNDROME | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-02-07 | — | — | US | disclosed |