Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2717245 | 0.76 | KCNN4 (0.38) | KCNN4KCNE1KCNQ1ALDH1A1CTNNB1 | |
| SCHEMBL13154113 | 0.67 | KCNN4 (0.42) | KCNN4KCNE1KCNQ1ALDH1A1HDAC6 | |
| SCHEMBL25263688 | 0.66 | KCNN4 (0.41) | KCNN4KCNE1KCNQ1ALDH1A1HDAC6 | |
| SCHEMBL12841736 | 0.65 | KCNN4 (0.46) | KCNN4KCNE1KCNQ1ALDH1A1HDAC6 | |
| SCHEMBL15480889 | 0.65 | KCNN4 (0.42) | KCNN4KCNE1KCNQ1ALDH1A1CTNNB1 | |
| SCHEMBL15145670 | 0.64 | KCNN4 (0.42) | KCNN4KCNE1KCNQ1NFKB1ERN1 | |
| SCHEMBL3366582 | 0.64 | KCNN4 (0.42) | KCNN4KCNE1KCNQ1CYP1A2GAA | |
| SCHEMBL10077236 | 0.64 | KCNN4 (0.44) | KCNN4KCNE1KCNQ1ALDH1A1HDAC6 | |
| SCHEMBL9220937 | 0.64 | IAPP (0.55) | ALDH1A1 | |
| SCHEMBL13232139 | 0.64 | ALDH1A1 (0.48) | KCNN4ALDH1A1HDAC6CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |