Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728628 | 0.82 | MAPT (0.35) | MAPT | |
| SCHEMBL730301 | 0.81 | MAPT (0.35) | MAPT | |
| SCHEMBL3070182 | 0.78 | MAPT (0.33) | MAPT | |
| SCHEMBL728670 | 0.77 | MAPT (0.33) | MAPT | |
| SCHEMBL10007006 | 0.77 | MAPT (0.33) | MAPT | |
| SCHEMBL16713052 | 0.76 | MAPT (0.32) | MAPT | |
| SCHEMBL11865413 | 0.76 | MAPT (0.41) | MAPTSLC22A6SMN1; SMN2TDP1 | |
| SCHEMBL2229574 | 0.74 | SMN1; SMN2 (0.43) | MAPTSLC22A6SMN1; SMN2 | |
| SCHEMBL11131045 | 0.73 | CA2 (0.42) | SMN1; SMN2TDP1 | |
| SCHEMBL5489086 | 0.73 | CA2 (0.42) | SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093486-A | Side effect reduction | AKZO N.V. (NL) | 1992-03-03 | — | — | US | disclosed |
| US-4981959-A | Modified cellulose for biocompatible dialysis membranes II and process for preparation thereof | AKZO N.V. (NL) | 1991-01-01 | — | — | US | disclosed |