Ethylene Glycol

Ethylene Glycol

SCHEMBL972941

OCCO.OCCO.[Fe+3].[Fe+3].[O-2].[O-2].[O-2]

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.71
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL8018930 0.86
Ethylene Glycol SCHEMBL19742049 0.86
Ethylene Glycol SCHEMBL8167017 0.86
Ethylene Glycol SCHEMBL8958886 0.86
Ethylene Glycol SCHEMBL2860028 0.86
Ethylene Glycol SCHEMBL8986295 0.86 TSHR (0.71) TSHRALDH1A1TDP1MAPK1
Ethylene Glycol SCHEMBL11049087 0.86
Ethylene Glycol SCHEMBL8013339 0.84 TSHR (1.00) TSHRALDH1A1TDP1MAPK1
Ethylene Glycol SCHEMBL3 0.84
Ethylene Glycol SCHEMBL1332716 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030232084-A1 Administering parenterally effective dose of iron oxide complex with polyol or polyether formulated in biocompatible liquid so that upon administration provides minimal detectable free iron in and minimal incidence of anaphylaxis COVIS PHARMA GMBH (CH) 2003-12-18 US claimed
US-9555133-B2 Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents AMAG PHARMACEUTICALS, INC. (US) 2017-01-31 US disclosed
US-8926947-B2 Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents AMAG PHARMACEUTICALS, INC. (US) 2015-01-06 US disclosed
US-20140296509-A1 Polyol and Polyether Iron Oxide Complexes as Pharmacological and/or MRI Contrast Agents AMAG PHARMACEUTICALS, INC. 2014-10-02 US disclosed
US-20140178310-A1 Polyol and Polyether Iron Oxide Complexes as Pharmacological and/or MRI Contrast Agents AMAG PHARMACEUTICALS, INC. 2014-06-26 US disclosed
US-8591864-B2 Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents AMAG PHARMACEUTICALS, INC. (US) 2013-11-26 US disclosed
US-8507207-B2 Recombinant nucleotide sequence, cell or vector containing the same and method for using cell containing the same to encode anti-polyethylene glycol monoclonal antibodies KAOHSIUNG MEDICAL UNIVERSITY (TW) 2013-08-13 US disclosed
US-8501158-B2 Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents AMAG PHARMACEUTICALS, INC. (US) 2013-08-06 US disclosed
US-20130121929-A1 Polyol and Polyether Iron Oxide Complexes as Pharmacological and/or MRI Contrast Agents AMAG PHARMACEUTICALS, INC. (US) 2013-05-16 US disclosed
US-20110144054-A1 Polyol and Polyether Iron Oxide Complexes as Pharmacological and/or MRI Contrast Agents AMAG PHARMACEUTICALS, INC. (US) 2011-06-16 US disclosed
US-20110064651-A1 RECOMBINANT NUCLEOTIDE SEQUENCE, CELL OR VECTOR CONTAINING THE SAME AND METHOD FOR USING CELL CONTAINING THE SAME TO ENCODE ANTI-POLYETHYLENE GLYCOL MONOCLONAL ANTIBODIES KAOHSIUNG MEDICAL UNIVERSITY (TW) 2011-03-17 US disclosed
US-7871597-B2 Administering parenterally effective dose of iron oxide complex with polyol or polyether formulated in biocompatible liquid so that upon administration provides minimal detectable free iron in and minimal incidence of anaphylaxis AMAG PHARMACEUTICALS, INC. (US) 2011-01-18 US disclosed
US-20030232084-A1 Administering parenterally effective dose of iron oxide complex with polyol or polyether formulated in biocompatible liquid so that upon administration provides minimal detectable free iron in and minimal incidence of anaphylaxis COVIS PHARMA GMBH (CH) 2003-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130121929-A1 Polyol and Polyether Iron Oxide Complexes as Pharmacological and/or MRI Contrast Agents TFRC, MSR1, CD47 TSHR 1635/4885ALDH1A1 3603/4885TDP1 4533/4885
US-20140178310-A1 Polyol and Polyether Iron Oxide Complexes as Pharmacological and/or MRI Contrast Agents TFRC, MSR1, CD47 TSHR 1635/4885ALDH1A1 3603/4885TDP1 4533/4885
US-20030232084-A1 Administering parenterally effective dose of iron oxide complex with polyol or polyether formulated in biocompatible liquid so that upon administration provides minimal detectable free iron in and minimal incidence of anaphylaxis TFRC, CMA1, CD69 TSHR 1893/4885ALDH1A1 4159/4885TDP1 4406/4885
US-20110144054-A1 Polyol and Polyether Iron Oxide Complexes as Pharmacological and/or MRI Contrast Agents TFRC, CD69, CMA1 TSHR 1487/4885ALDH1A1 4653/4885TDP1 4121/4885
US-20140296509-A1 Polyol and Polyether Iron Oxide Complexes as Pharmacological and/or MRI Contrast Agents TFRC, MSR1, CD47 TSHR 1635/4885ALDH1A1 3603/4885TDP1 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.