Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728892 | 0.88 | CYSLTR2 (0.40) | MAPTTDP1CYSLTR2CYSLTR1PPARG | |
| SCHEMBL3953955 | 0.82 | MAPT (0.43) | MAPTTDP1PPARGPPARA | |
| SCHEMBL5274212 | 0.80 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL9729015 | 0.79 | NPC1 (0.41) | — | |
| SCHEMBL9728623 | 0.78 | MAPT (0.58) | MAPTTDP1CYSLTR2CYSLTR1PPARG | |
| SCHEMBL17685400 | 0.78 | PPARG (0.48) | MAPTTDP1PPARGPPARA | |
| SCHEMBL9729444 | 0.77 | NPC1 (0.39) | CYSLTR2CYSLTR1 | |
| SCHEMBL8481540 | 0.75 | PTPN1 (0.50) | MAPTTDP1 | |
| SCHEMBL6936538 | 0.75 | PTGER1 (0.50) | MAPTTDP1 | |
| SCHEMBL13607855 | 0.74 | MAPT (0.57) | MAPTTDP1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155106-A | Reduced side effects | TERUMO KABUSHIKI KAISHA (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0400144-A1 | CYSTEAMINE DERIVATIVES AND ANTI-RHEUMATIC AGENT CONTAINING SAME | TERUMO KABUSHIKI KAISHA (JP) | 1990-12-05 | — | — | EP | disclosed |