Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729416 | 0.88 | MAPT (0.44) | CYSLTR2CYSLTR1PPARGPPARATDP1 | |
| SCHEMBL3956931 | 0.83 | MAPT (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1PPARG | |
| SCHEMBL9728468 | 0.79 | PPARG (0.48) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9729015 | 0.78 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1HSP90AA1 | |
| SCHEMBL9729444 | 0.76 | NPC1 (0.39) | CYSLTR2CYSLTR1NPC1RAB9AALDH1A1 | |
| SCHEMBL6938240 | 0.74 | CTSD (0.48) | NPC1RAB9ASMN1; SMN2TDP1MAPT | |
| SCHEMBL15096303 | 0.74 | KDM4E (0.42) | ALDH1A1TDP1MAPT | |
| SCHEMBL7867154 | 0.74 | GAA (0.48) | NPC1MAPK1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14899668 | 0.73 | TSHR (0.48) | ALDH1A1MAPT | |
| SCHEMBL4032438 | 0.72 | ALDH1A1 (0.51) | NPC1MAPK1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155106-A | Reduced side effects | TERUMO KABUSHIKI KAISHA (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0400144-A1 | CYSTEAMINE DERIVATIVES AND ANTI-RHEUMATIC AGENT CONTAINING SAME | TERUMO KABUSHIKI KAISHA (JP) | 1990-12-05 | — | — | EP | disclosed |