Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | TSHR | P16473 | 1/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.80 |
| ▸ | FNTA | P49354 | 6/20 | 0.61 |
| ▸ | FNTB | P49356 | 6/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729596 | 1.00 | TACR1 (0.80) | TACR1KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL8873856 | 0.91 | TACR1 (0.67) | TACR1KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL9729331 | 0.90 | TACR1 (0.68) | TACR1KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL9729902 | 0.90 | TACR1 (0.66) | TACR1KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL9730230 | 0.89 | TACR1 (0.65) | TACR1KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL4349316 | 0.89 | TACR1 (1.00) | TACR1KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL29373792 | 0.89 | TACR1 (1.00) | TACR1KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL7551020 | 0.89 | TACR1 (1.00) | TACR1KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL8460496 | 0.89 | TACR1 (1.00) | TACR1KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL14434342 | 0.89 | TACR1 (1.00) | TACR1KMT2AMEN1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |