Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754040 | 1.00 | LMNA (0.41) | LMNAPLGPLATGABRPGABRD | |
| SCHEMBL17676817 | 0.90 | PLG (0.34) | LMNAPLGPLATMME | |
| SCHEMBL8191503 | 0.89 | PLG (0.34) | LMNAPLGPLATPDE4APDE4B | |
| SCHEMBL5011525 | 0.82 | GAA (0.43) | TSHRMMEGAAALDH1A1KMT2A | |
| SCHEMBL4924414 | 0.82 | GAA (0.43) | TSHRMMEGAAALDH1A1KMT2A | |
| SCHEMBL13273683 | 0.82 | PLG (0.39) | LMNAPLGPLATGABRPGABRD | |
| SCHEMBL601347 | 0.81 | LMNA (0.45) | LMNAPLGPLATGABRPGABRD | |
| SCHEMBL8453791 | 0.81 | LMNA (0.45) | LMNAPLGPLATGABRPGABRD | |
| Cyclopropane Carboxylic Acid SCHEMBL28328958 | 0.81 | LMNA (0.45) | LMNAPLGPLATGABRPGABRD | |
| SCHEMBL13735804 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175290-A | Bronchodilator, cardiotonic agents | MARION MERRELL DOW INC. (US) | 1992-12-29 | — | — | US | disclosed |