SCHEMBL9729567

SCHEMBL9729567

CC(C)CON=C(Cc1cccnc1)c1ccc(Cl)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
ALDH1A1 P00352 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
LMNA P02545 3/20 0.42
HTT P42858 1/20 0.42
GAA P10253 1/20 0.41
IDO1 P14902 2/20 0.41
PGR P06401 1/20 0.41
CHRM2 P08172 1/20 0.41
CYP3A4 P08684 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
AR P10275 1/20 0.41
CYP2D6 P10635 1/20 0.41
CHRM1 P11229 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10906795 0.90 RAB9A (0.46) RAB9ANPC1ALDH1A1NFKB1NFKB2
SCHEMBL10907970 0.88 RAB9A (0.44) RAB9ANPC1ALDH1A1NFKB1NFKB2
SCHEMBL30697719 0.87 RAB9A (0.47) RAB9ANPC1ALDH1A1NFKB1NFKB2
SCHEMBL22696 0.87 RAB9A (0.47) RAB9ANPC1ALDH1A1NFKB1NFKB2
SCHEMBL22695 0.87 RAB9A (0.47) RAB9ANPC1ALDH1A1NFKB1NFKB2
SCHEMBL29586383 0.87 RAB9A (0.47) RAB9ANPC1ALDH1A1NFKB1NFKB2
SCHEMBL3066779 0.87 RAB9A (0.47) RAB9ANPC1ALDH1A1NFKB1NFKB2
Methyl Alcohol SCHEMBL28193600 0.86 DRD4 (0.47) RAB9ANPC1ALDH1A1NFKB1NFKB2
SCHEMBL28784244 0.86 RAB9A (0.46) RAB9ANPC1ALDH1A1NFKB1NFKB2
SCHEMBL9729525 0.85 RAB9A (0.42) RAB9ANPC1ALDH1A1NFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5171354-A Herbicides CIBA-GEIGY CORPORATION (US) 1992-12-15 US disclosed
EP-0445069-A1 Heterocyclic compounds CIBA-GEIGY AG (CH) 1991-09-04 EP disclosed