Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730240 | 0.82 | ERCC1 (0.40) | ALDH1A1 | |
| SCHEMBL434355 | 0.80 | IDO1 (0.48) | IDO1AGXTMAOBP2RX7MAPK8 | |
| SCHEMBL29836179 | 0.80 | SMN1; SMN2 (0.48) | IDO1AGXTMAOBP2RX7MAPK8 | |
| SCHEMBL3967997 | 0.80 | SMN1; SMN2 (0.48) | IDO1AGXTMAOBP2RX7MAPK8 | |
| SCHEMBL4659435 | 0.78 | IDO1 (0.43) | IDO1AGXTMAOBP2RX7MAPK8 | |
| SCHEMBL1699443 | 0.77 | MAOB (0.51) | IDO1AGXTMAOBP2RX7MAPK8 | |
| SCHEMBL15778100 | 0.76 | IDO1 (0.46) | IDO1AGXTMAOBP2RX7MAPK8 | |
| SCHEMBL20696508 | 0.74 | MAOB (0.46) | IDO1AGXTMAOBP2RX7MAPK8 | |
| SCHEMBL13329783 | 0.73 | MAPK8 (0.52) | IDO1AGXTMAOBP2RX7MAPK8 | |
| SCHEMBL1288294 | 0.72 | IDO1 (0.48) | IDO1AGXTMAOBP2RX7MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |