Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729674 | 0.82 | IDO1 (0.47) | ALDH1A1 | |
| SCHEMBL9729607 | 0.82 | HTT (0.50) | ERCC1ERCC4HTTMEN1KMT2A | |
| SCHEMBL434428 | 0.82 | ERCC1 (0.41) | ERCC1ERCC4SLC6A4KCNH2SLC6A2 | |
| SCHEMBL1525187 | 0.81 | ERCC1 (0.46) | ERCC1ERCC4HTTROCK2ROCK1 | |
| SCHEMBL13187181 | 0.79 | ERCC1 (0.39) | ERCC1ERCC4SLC6A4KCNH2SLC6A2 | |
| SCHEMBL19030836 | 0.79 | ERCC1 (0.46) | ERCC1ERCC4HTR2AKMT2AL3MBTL1 | |
| SCHEMBL9729770 | 0.79 | ALDH1A1 (0.42) | SLC6A4KCNH2HTR2AHTTKMT2A | |
| SCHEMBL6505166 | 0.74 | IDO1 (0.41) | SLC6A4KCNH2SLC6A2HTR2AHTT | |
| SCHEMBL19030893 | 0.73 | POLQ (0.43) | ERCC1ERCC4SLC6A4SLC6A2HTR2A | |
| SCHEMBL29434734 | 0.73 | KEAP1 (0.50) | ERCC1ERCC4HTR2ATP53HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |