Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731348 | 1.00 | TSHR (0.37) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL873337 | 1.00 | TSHR (0.37) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL9730288 | 1.00 | TSHR (0.37) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL9730528 | 1.00 | TSHR (0.37) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL9730272 | 0.93 | DNM1 (0.43) | ALDH1A1DNM1SPHK1 | |
| SCHEMBL9730929 | 0.91 | DNM1 (0.47) | DNM1PLA2G4BSPHK1 | |
| SCHEMBL9730541 | 0.91 | DNM1 (0.47) | DNM1PLA2G4BSPHK1 | |
| SCHEMBL9730332 | 0.91 | DNM1 (0.47) | DNM1PLA2G4BSPHK1 | |
| SCHEMBL9731222 | 0.91 | DNM1 (0.47) | DNM1PLA2G4BSPHK1 | |
| SCHEMBL9730012 | 0.91 | DNM1 (0.47) | DNM1PLA2G4BSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167863-A | Ferroelectricity; electrooptic switches | HITACHI, LTD. (JP) | 1992-12-01 | — | — | US | disclosed |
| EP-0322862-A2 | Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators | HITACHI, LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |