Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3504284 | 0.97 | — | — | |
| SCHEMBL531227 | 0.88 | LMNA (0.53) | LMNATHRBHSD17B10TDP1 | |
| Butane SCHEMBL15526311 | 0.85 | LMNA (0.80) | LMNATHRB | |
| Ammonia Solution, Strong SCHEMBL1292759 | 0.85 | — | — | |
| SCHEMBL3453066 | 0.85 | — | — | |
| Ammonia Solution, Strong SCHEMBL15232243 | 0.85 | LMNA (0.92) | LMNATHRB | |
| Butane SCHEMBL49299 | 0.82 | LMNA (0.86) | LMNATHRB | |
| Butane SCHEMBL1866739 | 0.82 | LMNA (0.86) | LMNATHRB | |
| SCHEMBL2094168 | 0.82 | LMNA (1.00) | LMNATHRB | |
| SCHEMBL9459 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171753-A | Derivatives of 2-amino-1-phenylethanol having antiulcer activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-12-15 | — | — | US | disclosed |