SCHEMBL9730109

SCHEMBL9730109

N#CC(C#N)=C(S)S.[KH].[KH]

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5572445 0.96
SCHEMBL8554549 0.92
Methane SCHEMBL7920519 0.92
SCHEMBL9188910 0.92 KDM4E (0.30) KDM4EMEN1LMNAMAPTKMT2A
Maleic Acid SCHEMBL28461578 0.74 TSHR (0.45) MEN1KMT2A
SCHEMBL28464454 0.69 CA1 (0.40) KDM4EMEN1LMNAMAPTKMT2A
SCHEMBL26931 0.69 CA1 (0.40) KDM4EMEN1LMNAMAPTKMT2A
SCHEMBL11764902 0.65 KDM4E (0.37) KDM4EMEN1LMNAMAPTKMT2A
SCHEMBL852413 0.65 KDM4E (0.37) KDM4EMEN1LMNAMAPTKMT2A
SCHEMBL28456561 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5171743-A Compounds composition and use of substituted 1,3-dithiolo- and 1,4-dithino-pyridines as an antimicrobial THE DOW CHEMICAL COMPANY (US) 1992-12-15 US disclosed
US-3956291-A BACTERICIDES AMERICAN HOME PRODUCTS CORPORATION (US) 1976-05-11 US disclosed