Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730197 | 0.94 | TACR1 (0.53) | TACR1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL9730461 | 0.91 | TSHR (0.47) | TACR1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL9730899 | 0.88 | TACR1 (0.55) | TACR1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL9729942 | 0.88 | TACR1 (0.49) | TACR1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL9729441 | 0.88 | TACR1 (0.52) | TACR1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL9730495 | 0.85 | TACR1 (0.55) | TACR1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL9729715 | 0.85 | MEN1 (0.47) | TACR1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL9729691 | 0.84 | TACR1 (0.53) | TACR1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL9730151 | 0.84 | TACR1 (0.52) | TACR1MAPTMEN1CYP3A4TSHR | |
| SCHEMBL9730103 | 0.84 | MAPT (0.56) | TACR1MAPTMEN1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |