Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730197 | 0.92 | TACR1 (0.53) | TACR1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL9730566 | 0.91 | TACR1 (0.54) | TACR1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL9730365 | 0.88 | TACR1 (0.51) | TACR1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL9730495 | 0.85 | TACR1 (0.55) | TACR1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL9730371 | 0.84 | TACR1 (0.54) | TACR1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL9729350 | 0.83 | TACR1 (0.53) | TACR1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL9730461 | 0.83 | TSHR (0.47) | TACR1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL9729715 | 0.83 | MEN1 (0.47) | TACR1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL9729223 | 0.83 | TACR1 (0.56) | TACR1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL9730151 | 0.82 | TACR1 (0.52) | TACR1MEN1MAPTKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |