Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730495 | 0.86 | TACR1 (0.55) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730197 | 0.85 | TACR1 (0.53) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729350 | 0.85 | TACR1 (0.53) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729223 | 0.84 | TACR1 (0.56) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730899 | 0.84 | TACR1 (0.55) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730151 | 0.84 | TACR1 (0.52) | TACR1MEN1CYP3A4MAPTTSHR | |
| Iodide SCHEMBL9729835 | 0.83 | TACR1 (0.52) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730114 | 0.83 | TACR1 (0.69) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730566 | 0.82 | TACR1 (0.54) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729555 | 0.82 | TACR1 (0.50) | TACR1MEN1CYP3A4MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |