SCHEMBL9730564

SCHEMBL9730564

COc1cc(OC)cc(C(Cl)Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
CYP1A1 P04798 7/20 0.44
CYP1B1 Q16678 7/20 0.44
CYP1A2 P05177 4/20 0.39
CYP3A4 P08684 3/20 0.39
CYP2E1 P05181 2/20 0.39
CYP2C8 P10632 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2A6 P11509 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP4B1 P13584 2/20 0.39
CYP2B6 P20813 2/20 0.39
CYP3A5 P20815 2/20 0.39
CYP2A7 P20853 2/20 0.39
CYP3A7 P24462 2/20 0.39
CYP2F1 P24903 2/20 0.39
CYP2C18 P33260 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2J2 P51589 2/20 0.39
CYP4F2 P78329 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30934876 0.84 ALDH1A1 (0.58) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL28245392 0.80 ALDH1A1 (0.52) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL16372527 0.79 ALDH1A1 (0.58) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL5263393 0.77 AOC3 (0.50) ALDH1A1CYP3A4L3MBTL1CA1CA2
1,3,5-Trimethoxybenzene SCHEMBL28493 0.76 ALDH1A1 (1.00) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL40553 0.76 ALDH1A1 (0.61) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL24406798 0.75 ALDH1A1 (0.52) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL4716539 0.75 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL903695 0.74 ALDH1A1 (0.58) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL9318733 0.74 CA1 (0.58) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819195-B Preparation method of pterostilbene 三原润禾生物科技有限公司 2024-01-05 CN disclosed
CN-105829304-A N, n substituted piperidinamine compounds, and preparation method and usage thereof 中国人民解放军军事医学科学院毒物药物研究所 2016-08-03 CN disclosed
US-5126461-A Silica in organic solution SHELL RESEARCH LIMITED (GB) 1992-06-30 US disclosed
EP-0432818-A2 Process for opening cyclopropane rings SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-06-19 EP disclosed