Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2902591 | 0.82 | SIGMAR1 (0.52) | CYP1A2SIGMAR1GAACYP2D6MC4R | |
| SCHEMBL2734368 | 0.81 | SIGMAR1 (0.54) | CYP1A2SIGMAR1GAAALDH1A1TDP1 | |
| SCHEMBL30322312 | 0.78 | CYP1A2 (0.57) | CYP1A2ALOX15CYP2C19SIGMAR1MAPT | |
| SCHEMBL28677044 | 0.75 | CYP1A2 (0.62) | CYP1A2ALOX15CYP2C19SIGMAR1MAPT | |
| SCHEMBL2438031 | 0.74 | SIGMAR1 (0.60) | SIGMAR1GAAALDH1A1TDP1F2 | |
| SCHEMBL13037358 | 0.74 | SIGMAR1 (0.46) | CYP1A2SIGMAR1MAPTGAAALDH1A1 | |
| SCHEMBL18134602 | 0.73 | CYP1A2 (1.00) | CYP1A2ALOX15CYP2C19SIGMAR1MAPT | |
| SCHEMBL2012135 | 0.71 | GAA (0.55) | SIGMAR1GAACYP2D6ALDH1A1ELANE | |
| SCHEMBL5075479 | 0.71 | SIGMAR1 (0.56) | SIGMAR1MAPTGAAALDH1A1TDP1 | |
| SCHEMBL2962712 | 0.71 | FUCA1 (0.58) | SIGMAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |