Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 14/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365360 | 1.00 | KDM1A (0.48) | KDM1AMAOBMAPK1MAOASLC6A2 | |
| SCHEMBL9365368 | 1.00 | KDM1A (0.48) | KDM1AMAOBMAPK1MAOASLC6A2 | |
| SCHEMBL9730800 | 1.00 | KDM1A (0.48) | KDM1AMAOBMAPK1MAOASLC6A2 | |
| SCHEMBL9366332 | 0.88 | GRIA2 (0.39) | KDM1AMAOBGRIA2 | |
| SCHEMBL9731557 | 0.88 | GRIA2 (0.39) | KDM1AMAOBGRIA2 | |
| SCHEMBL9366345 | 0.88 | GRIA2 (0.39) | KDM1AMAOBGRIA2 | |
| SCHEMBL9731554 | 0.88 | GRIA2 (0.39) | KDM1AMAOBGRIA2 | |
| SCHEMBL9732745 | 0.87 | KDM1A (0.34) | KDM1AMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9732740 | 0.87 | KDM1A (0.34) | KDM1AMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9365423 | 0.87 | KDM1A (0.34) | KDM1AMAOBSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5160661-A | DIOXANYLPYRIDINE | HOFFMANN-LA ROCHE INC. (US) | 1992-11-03 | — | — | US | disclosed |