Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119253 | 0.90 | AR (0.44) | ARMEN1MAPTKMT2ATDP1 | |
| SCHEMBL669781 | 0.78 | TRIM24 (0.54) | ARMEN1KMT2ATDP1ECE2 | |
| SCHEMBL668600 | 0.78 | TRIM24 (0.54) | ARMEN1KMT2ATDP1ECE2 | |
| SCHEMBL31194371 | 0.78 | TRIM24 (0.54) | ARMEN1KMT2ATDP1ECE2 | |
| SCHEMBL7120412 | 0.77 | ESR1 (0.33) | AR | |
| SCHEMBL27727315 | 0.76 | TRIM24 (0.52) | ARMEN1KMT2ATDP1ECE2 | |
| Formamide SCHEMBL9732252 | 0.76 | ALDH1A1 (0.40) | MEN1MAPTKMT2AGAAHPGD | |
| SCHEMBL2096786 | 0.75 | ALDH1A1 (0.46) | MEN1MAPTKMT2ATDP1MITF | |
| SCHEMBL29434206 | 0.75 | ALDH1A1 (0.46) | MEN1MAPTKMT2ATDP1MITF | |
| SCHEMBL10466277 | 0.75 | TRIM24 (0.50) | ARMEN1KMT2ATDP1ECE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | claimed |
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |