Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.35 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247618 | 0.75 | SLC2A1 (0.45) | TDP2SLC2A1 | |
| SCHEMBL19537465 | 0.74 | — | — | |
| SCHEMBL22805 | 0.72 | MAPT (0.46) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| SCHEMBL18992911 | 0.70 | MAPT (0.41) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| SCHEMBL199946 | 0.68 | XIAP (0.45) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| SCHEMBL30003056 | 0.67 | PADI1 (0.39) | MAPTHTTTP53SMN1; SMN2NSD2 | |
| SCHEMBL28880688 | 0.67 | NSD2 (0.41) | MAPTHTTNSD2PTPN1HKDC1 | |
| SCHEMBL11658103 | 0.67 | MAPT (0.41) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| SCHEMBL4964070 | 0.66 | NSD2 (0.43) | MAPTHTTNSD2PTPN1HKDC1 | |
| SCHEMBL21819582 | 0.66 | NSD2 (0.43) | MAPTHTTNSD2PTPN1HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104874-A | Cyclooxygenase and lipoxygenase inhibitob | PFIZER INC. (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0443710-A1 | Benzoquinone antiallergy and antiinflammatory agents | PFIZER INC. (US) | 1991-08-28 | — | — | EP | disclosed |