Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97314 | 1.00 | PAM (0.48) | PAMSIGMAR1IDO1HTR2AMAOB | |
| SCHEMBL97321 | 0.88 | PAM (0.46) | PAMSIGMAR1IDO1HTR2AMAOB | |
| SCHEMBL97320 | 0.88 | PAM (0.46) | PAMSIGMAR1IDO1HTR2AMAOB | |
| SCHEMBL97133 | 0.86 | PAM (0.44) | PAMSIGMAR1IDO1HTR2A | |
| SCHEMBL97134 | 0.86 | PAM (0.44) | PAMSIGMAR1IDO1HTR2A | |
| SCHEMBL9232454 | 0.85 | PAM (0.43) | PAMSIGMAR1IDO1HTR2A | |
| SCHEMBL9232451 | 0.85 | PAM (0.43) | PAMSIGMAR1IDO1HTR2A | |
| SCHEMBL5485528 | 0.85 | PAM (0.43) | PAMSIGMAR1IDO1HTR2A | |
| SCHEMBL5485529 | 0.85 | PAM (0.43) | PAMSIGMAR1IDO1HTR2A | |
| SCHEMBL2090495 | 0.82 | CYP1A2 (0.44) | MAOBGRIK1GRIK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793379-B | Cinnamon acetal diglycidyl ether and preparation method and application thereof | 温州大学 | 2021-02-19 | — | — | CN | claimed |
| CN-108178803-B | Preparation of drug-loaded cinnamaldehyde-glucan polymer self-assembled nanoparticles and anti-tumor application thereof | 温州医科大学 | 2020-03-10 | — | — | CN | claimed |
| CN-113384566-A | Application of cinnamaldehyde and derivatives thereof as histone deacetylase agonists | 广州中医药大学(广州中医药研究院) | 2021-09-14 | — | — | CN | disclosed |
| CN-107793379-B | Cinnamon acetal diglycidyl ether and preparation method and application thereof | 温州大学 | 2021-02-19 | — | — | CN | disclosed |
| CN-108623807-B | Responsive polymer nano particle based on cinnamaldehyde and preparation method thereof | 温州大学 | 2020-12-29 | — | — | CN | disclosed |
| CN-107759788-B | Cinnamic aldehyde-based polymer with acid and photodegradable properties and preparation method thereof | 温州大学 | 2020-10-27 | — | — | CN | disclosed |
| CN-111437212-A | Prebiotic oral care compositions containing amino acids | 高露洁-棕榄公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-106061492-B | Prebiotic oral care compositions containing amino acids | 高露洁-棕榄公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-108178803-B | Preparation of drug-loaded cinnamaldehyde-glucan polymer self-assembled nanoparticles and anti-tumor application thereof | 温州医科大学 | 2020-03-10 | — | — | CN | disclosed |
| CN-104144786-B | Surface protective plate, e-machine and the manufacture method of e-machine parts | 木本股份有限公司 | 2016-11-02 | — | — | CN | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |
| US-5071856-A | CARBOSTYRIL DERIVATIVES AND SALTS THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| CN-1046529-A | Carbostyril derivative | OTSUKA PHARMA CO LTD (JP) | 1990-10-31 | — | — | CN | disclosed |
| US-4886809-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0255134-A2 | Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-03 | — | — | EP | disclosed |
| US-4514401-A | CARDIOTONICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-04-30 | — | — | US | disclosed |
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |