Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15928202 | 0.81 | NPC1 (0.61) | NPC1RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL7625975 | 0.79 | NPC1 (0.54) | NPC1RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL14868801 | 0.79 | NPC1 (0.50) | NPC1RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL11595335 | 0.79 | MEN1 (0.66) | NPC1RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL12851364 | 0.79 | NPC1 (0.79) | NPC1RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL4681740 | 0.78 | NPC1 (0.53) | NPC1RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL5068038 | 0.78 | NPC1 (0.61) | NPC1RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL4023664 | 0.78 | NPC1 (0.61) | NPC1RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL10997197 | 0.77 | GLS (0.57) | NPC1RAB9AALDH1A1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL30496701 | 0.77 | NPC1 (0.51) | NPC1RAB9AALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009446-A1 | OLIGOMER-GUANIDINE CLASS CONJUGATES | NEKTAR THERAPEUTICS (US) | 2011-01-13 | — | — | US | claimed |
| WO-2009089053-A1 | OLIGOMER-GUANIDINE CLASS CONJUGATES | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-07-16 | — | — | WO | claimed |
| US-20110009446-A1 | OLIGOMER-GUANIDINE CLASS CONJUGATES | NEKTAR THERAPEUTICS (US) | 2011-01-13 | — | — | US | disclosed |
| WO-2009089053-A1 | OLIGOMER-GUANIDINE CLASS CONJUGATES | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009446-A1 | OLIGOMER-GUANIDINE CLASS CONJUGATES | GMPS, OGT, GBA1 | NPC1 162/4885RAB9A 1112/4885ALDH1A1 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.