L-Phenylalaninol

L-Phenylalaninol

SCHEMBL9733120

COC.N[C@H](CO)Cc1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.64
ANPEP P15144 1/20 0.55
SLC6A2 P23975 2/20 0.54
TAAR1 Q96RJ0 2/20 0.54
MAOA P21397 1/20 0.54
SLC6A4 P31645 1/20 0.54
SLC6A3 Q01959 1/20 0.54
SIGMAR1 Q99720 1/20 0.54
CYP2A6 P11509 1/20 0.54
ADORA2A P29274 1/20 0.54
ADORA1 P30542 1/20 0.54
TRPA1 O75762 1/20 0.53
LAP3 P28838 1/20 0.51
SCN4A P35499 2/20 0.50
CYP2D6 P10635 1/20 0.50
ALPI P09923 1/20 0.48
PKM P14618 1/20 0.48
PTGS1 P23219 1/20 0.48
XIAP P98170 1/20 0.48
SLC7A5 Q01650 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
L-Phenylalaninol SCHEMBL5967085 0.98 EPHX1 (0.61) EPHX1ANPEPSLC6A2TAAR1MAOA
L-Phenylalaninol SCHEMBL81769 0.91 EPHX1 (0.76) EPHX1ANPEPSLC6A2TAAR1MAOA
L-Phenylalaninol SCHEMBL7422483 0.91 EPHX1 (0.76) EPHX1ANPEPSLC6A2TAAR1MAOA
L-Phenylalaninol SCHEMBL87692 0.91 EPHX1 (0.76) EPHX1ANPEPSLC6A2TAAR1MAOA
L-Phenylalaninol SCHEMBL2521 0.91 EPHX1 (0.76) EPHX1ANPEPSLC6A2TAAR1MAOA
L-Phenylalaninol SCHEMBL177073 0.91 EPHX1 (0.76) EPHX1ANPEPSLC6A2TAAR1MAOA
L-Phenylalaninol SCHEMBL7252746 0.89 EPHX1 (0.73) EPHX1ANPEPSLC6A2TAAR1MAOA
L-Phenylalaninol SCHEMBL30996912 0.89 EPHX1 (0.73) EPHX1ANPEPSLC6A2TAAR1MAOA
L-Phenylalaninol SCHEMBL15467495 0.89 EPHX1 (0.73) EPHX1ANPEPSLC6A2TAAR1MAOA
L-Phenylalaninol SCHEMBL31229492 0.89 EPHX1 (0.73) EPHX1ANPEPSLC6A2TAAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992007829-A1 INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS THE UPJOHN COMPANY (US) 1992-05-14 WO disclosed