Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417108 | 1.00 | MAPT (0.49) | MAPTMEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL9733142 | 1.00 | MAPT (0.49) | MAPTMEN1KMT2AHSD17B10CYP1A2 | |
| SCHEMBL12417099 | 0.90 | ALDH1A1 (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL9733108 | 0.90 | ALDH1A1 (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL9733114 | 0.90 | ALDH1A1 (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL9732967 | 0.85 | MAPT (0.53) | MAPTCYP1A2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL9732965 | 0.85 | MAPT (0.53) | MAPTCYP1A2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL12417113 | 0.85 | MAPT (0.53) | MAPTCYP1A2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL12417127 | 0.83 | CYP1A2 (0.51) | MAPTKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12417128 | 0.83 | ALDH1A1 (0.46) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013846-A1 | PYRIMIDINYL- AND TRIAZINYLSALICYL- AND -PICOLINYLALDEHYDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-08-20 | — | — | WO | claimed |
| WO-1992013846-A1 | PYRIMIDINYL- AND TRIAZINYLSALICYL- AND -PICOLINYLALDEHYDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-08-20 | — | — | WO | disclosed |