Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733606 | 0.82 | PKM (0.44) | PKMCYP4F2CYP4A11NLRP3MMP8 | |
| SCHEMBL12258106 | 0.81 | MAPT (0.47) | SMN1; SMN2LMNAKMT2ACYP3A4CYP2D6 | |
| SCHEMBL9731499 | 0.80 | PKM (0.42) | PKMCYP4F2CYP4A11NLRP3MMP8 | |
| SCHEMBL28670364 | 0.78 | PKM (0.54) | PKMCYP4F2CYP4A11SMN1; SMN2LMNA | |
| SCHEMBL23781411 | 0.78 | HTT (0.44) | LMNANPSR1CYP3A4CYP2D6 | |
| SCHEMBL19960628 | 0.78 | PKM (0.48) | PKMCYP4F2CYP4A11NLRP3SMN1; SMN2 | |
| SCHEMBL68340 | 0.78 | PKM (0.60) | PKMCYP4F2CYP4A11NLRP3SMN1; SMN2 | |
| SCHEMBL19953657 | 0.77 | PKM (0.47) | PKMCYP4F2CYP4A11NLRP3SMN1; SMN2 | |
| SCHEMBL6878047 | 0.74 | PKM (0.57) | PKMCYP4F2CYP4A11NLRP3SMN1; SMN2 | |
| SCHEMBL31424953 | 0.74 | PKM (0.57) | PKMCYP4F2CYP4A11NLRP3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106844-A | Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine antiarrhythmic agents | STERLING DRUG INC. (US) | 1992-04-21 | — | — | US | disclosed |